new discovery may lead to more effective acne treatments 2

Scientists Ascertain Genetic Accomplish-up of Acne Bacterium

Scientists accept continued accepted that the bacterium Propionibacterium
acnes (P. acnes) plays a leading role in the adding to of acne
vulgaris, the scourge afflicting some 80% of teenagers and abounding
adults as able-bodied. A normally innocuous microbe that lives in the
hair follicles of every person, P. acnes helps statement acne when
the follicles alter to plugged with sebum, a accustomed oil produced
by the body.

Recently a accumulation of German scientists, led by microbiologist Dr.
Holger Brueggemann, mapped the genetic code of the P. acnes
microbe. They discovered that it has a circular chromosome with
2,333 genes, abounding of which had surprising destructive abilities.
“We were astonished to beam how abounding genes were involved in
degrading the human tissue,” said Dr. Brueggemann.

For archetype, the researchers activate that P. acnes contains
enzymes agnate to those in so-called “flesh-eating” bacteria
that abort human tissue. It again has enzymes that breach down
the skin and statement it as its aliment supply. It contains genes that
secrete substances that annihilate competitors, according to harmful bacteria
and fungi, in much the selfsame road as pathogens according to
tuberculosis and diphtheria. And it uses a defense manoeuvre accepted
as “phase variation” that helps it escape advance by the human
unsusceptible system.

Advanced Acne Treatments May Be Possible

What does this beggarly for acne sufferers?

Scientists accept continued believed that acne results when pores
alter to plugged by bits of dead, flaking skin and sebum. These
plugged pores fill with oil, which the P. acnes microbe then
feeds on while releasing certain chemicals and enzymes. These
enzymes attract achromatic blood cells, causing inflammation, redness
and pimples we call acne. Adolescents are added generally afflicted
by acne as during that age period added of this oil is
produced, thanks to hormonal changes in the body at that age.

Most traditional acne treatments today are designed to either
annihilate bacteria or to prevent pores from becoming plugged.
However, P. acnes has developed resistance to abounding of the
antibiotics used to treat acne, leading scientist to seek newer,
added able treatments.

This advanced discovery by Dr. Brueggemann’s research accumulation will advance
to a bigger compassionate of the P. acnes bacterium and how it
operates in causing or aiding the outbreak of acne. This
adeptness may able-bodied advance to advanced approaches to treating acne by
bigger targetting the enzyme systems of P. acnes and relieving
the affliction and suffering of teens and adults with acne.

About the Author

Diane Darling, COTA/L, is a licensed and certified occupational
therapy assistant who works with learning-challenged children.
She again has a eager absorption in issues of skin affliction and acne,
and maintains the Treating Acne website located at

Originall posted June 29, 2012